The product of 20 years of study, this book sums up editor Ugo Ripamonti’s research into the osteogenic activity of the TGF-β growth factor family, particularly in primates. It explores how the three mammalian TGF-β isoforms have the potential to shed light on the apparent redundancy of bone induction signaling. The book contributes to the fascinating history of BMP and TGF-β research at the intersection of molecular biology, tissue induction, bone regeneration, and craniofacial surgery. It provides a revolutionary awakening to new possibilities in skeletal reconstruction, tissue engineering, and molecular and cellular biology.
