Itgivesmegreatpleasuretoeditthisbook. Thegenesisofthisbookgoes backtotheconferenceheldattheUniversityofBolognainJune1999,on collaborativeworkbetweentheUniversityofCaliforniaatBerkeleyandthe UniversityofBologna. Theoriginalideawastoinvitesomespeakersatthe conferencetosubmitarticlestothebook. Thescopeofthebookwaslater- hancedand,inthepresentform,itisacompilationofsomeoftherecentwork usinggeometricpartialdi?erentialequationsandthelevelsetmethodology inmedicalandbiomedicalimageanalysis. Thesynopsisofthebookisasfollows:Inthe?rstchapter,R. Malladi andJ. A. Sethianpointtotheoriginsoftheuseoflevelsetmethodsand geometricPDEsforsegmentation,andpresentfastmethodsforshapes- mentationinbothmedicalandbiomedicalimageapplications. InChapter 2,C. OrtizdeSolorzano,R. Malladi,andS. J. Lockettdescribeabodyof workthatwasdoneoverthepastcoupleofyearsattheLawrenceBerkeley NationalLaboratoryonapplicationsoflevelsetmethodsinthestudyand understandingofconfocalmicroscopeimagery. TheworkinChapter3byA. Sarti,C. Lamberti,andR. Malladiaddressestheproblemofunderstanding di?culttimevaryingechocardiographicimagery. Thisworkpresentsvarious levelsetmodelsthataredesignedto?tavarietyofimagingsituations,i. e. timevarying2D,3D,andtimevarying3D. InChapter4,L. VeseandT. F. Chanpresentasegmentationmodelwithoutedgesandalsoshowextensions totheMumford-Shahmodel. Thismodelisparticularlypowerfulincertain applicationswhencomparisonsbetweennormalandabnormalsubjectsis- quired. Next,inChapter5,A. EladandR. Kimmelusethefastmarching methodontriangulateddomaintobuildatechniquetounfoldthecortexand mapitontoasphere. Thistechniqueismotivatedinpartbynewadvances infMRIbasedneuroimaging. InChapter6,T. DeschampsandL. D. Cohen presentaminimalpathbasedmethodofgroupingconnectedcomponentsand showcleverapplicationsinvesseldetectionin3Dmedicaldata. Finally,in Chapter7,A. Sarti,K. Mikula,F. Sgallari,andC. Lamberti,describean- linearmodelfor?lteringtimevarying3Dmedicaldataandshowimpressive resultsinbothultrasoundandechoimages. Ioweadeb
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