Foundations.- Getting started with Isabelle.- Advanced methods.- Basic use of Isabelle.- Proof management: The subgoal module.- Tactics.- Tacticals.- Theorems and forward proof.- Theories, terms and types.- Defining logics.- Syntax transformations.- Substitution tactics.- Simplification.- The classical reasoner.- Basic concepts.- First-order logic.- Zermelo-Fraenkel set theory.- Higher-order logic.- First-order sequent calculus.- Constructive Type Theory.- Syntax of Isabelle Theories.